Cryptic crossword clue
All fools, they say, take one drug among others 5

The most common and most likely answer to this crossword clue is the 5 letter word POETS

I've seen this crossword clue in The Guardian
P
O
E
T
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does POETS mean?

POETS noun
  1. A person who writes poems.
  2. A person with a creative or romantic imagination.

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