Cryptic crossword clue
All-male relationship as couple heartlessly broken up by sultanate 8

The most common and most likely answer to this crossword clue is the 8 letter word BROMANCE

B
R
O
M
A
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Buddy explains!

The straight part
We know that "All-male relationship" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case all-male relationship = bromance.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BROMANCE mean?

BROMANCE noun
  1. A close but non-sexual relationship between men.

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