Cryptic crossword clue
American envoy, say, circumventing guide mostly 6

The most common and most likely answer to this crossword clue is the 6 letter word EPILOG

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The straight part
We know that "American envoy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case american envoy = epilog.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EPILOG mean?

EPILOG noun
  1. A short speech, spoken directly at the audience at the end of a play
  2. The performer who gives this speech
  3. A brief oration or script at the end of a literary piece; an afterword
  4. A component of a computer program that prepares the computer to return from a routine.

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