Cryptic crossword clue
American fly-by-night books in place of Douglas and Henry 2,4

The most common and most likely answer to this crossword clue is the 2 plus 4 letter word IO MOTH

I
O
M
O
T
H

Buddy explains!

The straight part
We know that "American fly-by-night" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case american fly-by-night = io moth.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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