Cryptic crossword clue
American native travelled on, we hear, with messenger 10

The most common and most likely answer to this crossword clue is the 10 letter word ROADRUNNER

I've seen this crossword clue in The Times
R
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Buddy explains!

The straight part
We know that "American native" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case american native = roadrunner.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ROADRUNNER mean?

ROADRUNNER noun
  1. Either of two species of bird in the genus Geococcyx of the cuckoo family, native to North and Central America. They are fast runners.

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