The most common and most likely answer to this crossword clue is the 4 letter word ODOR
I've seen this crossword clue in The Daily Telegraph
O
D
O
R
More clues leading to the result ODOR
- Old designer leaving Italy to make scent for Americans
- Blood oranges exuding scent of Florida
- Smell from US neighbourhood originated within
- American perfume’s socially unacceptable smell
- Smell blood-orange segment
- Skunk’s defense in good order
- Stench from oxygen bar? Revolting
- Have too much “hospital area” smell
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ODOR mean?
ODOR noun- Any smell, whether fragrant or offensive.
- A strong, pervasive quality.
- Esteem.
- Something which produces a scent; incense, a perfume.