Cryptic crossword clue
American unit destroying half of what’s written 5

The most common and most likely answer to this crossword clue is the 5 letter word LITER

I've seen this crossword clue in Financial Times
L
I
T
E
R


Buddy explains!

The straight part
We know that "American unit" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case american unit = liter.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LITER mean?

LITER noun
  1. The metric unit of fluid measure, equal to one cubic decimetre. Symbols: l, L, ℓ
  2. A measure of volume equivalent to a litre.

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