Cryptic crossword clue
Amusing part of the zodiac is one that provides guidance for those at sea 10

The most common and most likely answer to this crossword clue is the 10 letter word LIGHTHOUSE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "one that provides guidance for those at sea" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one that provides guidance for those at sea = lighthouse.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LIGHTHOUSE mean?

LIGHTHOUSE noun
  1. A tower or other structure exhibiting a light or lights to warn or guide sailors.

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