Cryptic crossword clue
An idiot is stifling man’s opposition 10

The most common and most likely answer to this crossword clue is the 10 letter word ANTITHESIS

I've seen this crossword clue in The Guardian
A
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Buddy explains!

The straight part
We know that "opposition" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case opposition = antithesis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANTITHESIS mean?

ANTITHESIS noun
  1. A proposition that is the diametric opposite of some other proposition.
  2. A device by which two contrasting ideas are juxtaposed in parallel form.

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