The most common and most likely answer to this crossword clue is the 4 letter word TUBA
I've seen this crossword clue in The Times
T
U
B
A
More clues leading to the result TUBA
- Instrument neighbour put up
- This musical instrument has upset neighbour
- VAT on article? Blow me!
- An objection over large orchestral piece?
- VAT on a musical instrument
- University visits as yet unscheduled, blow it!
- Audience’s first objection backing brass instrument
- Instrument taken up by absolute beginners
- Join up with part of orchestra
- Lean on inverted instrument
Buddy explains!

The straight part
We know that "large orchestral piece" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case large orchestral piece = tuba.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TUBA mean?
TUBA noun- A large brass musical instrument, usually in the bass range, played through a vibration of the lips upon the mouthpiece and fingering of the keys.
- A type of Roman military trumpet, distinct from the modern tuba.
- A large reed stop in organs.
- A Malayan plant whose roots are a significant source of rotenone, Derris malaccensis.
- A reddish palm wine made from coconut or nipa sap.
- A tube or tubular organ.