The most common and most likely answer to this crossword clue is the 3 letter word E.G
I've seen this crossword clue in Independent
E
.
G
More clues leading to the result E.G
Buddy explains!
The straight part
We know that "Anagram of/Anagram of/(combination of)" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case anagram of/anagram of/(combination of) = e.g.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.