Cryptic crossword clue
Angry at having sick around the place

The most common and most likely answer to this crossword clue is the 10 letter word DISPLEASED

I've seen this crossword clue in The Guardian
D
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D

Buddy explains!

The straight part
We know that "Angry" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case angry = displeased.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISPLEASED mean?

DISPLEASED verb
  1. To make not pleased; to cause a feeling of disapprobation or dislike in; to be disagreeable to; to vex slightly.
  2. To give displeasure or offense.
  3. To fail to satisfy; to miss of.
DISPLEASED adjective
  1. Not pleased or happy with something.

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