Cryptic crossword clue
Angry guards manipulate supply for crop sustenance 8

The most common and most likely answer to this crossword clue is the 8 letter word IRRIGATE

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Buddy explains!

The straight part
We know that "supply for crop sustenance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case supply for crop sustenance = irrigate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IRRIGATE mean?

IRRIGATE verb
  1. To supply (farmland) with water, by building ditches, pipes, etc.
  2. To clean (a wound) with a fluid.

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