Cryptic crossword clue
Annoys with extracted lead chemicals 6

The most common and most likely answer to this crossword clue is the 6 letter word ESTERS

E
S
T
E
R
S

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does ESTERS mean?

ESTERS noun
  1. A compound most often formed by the condensation of an alcohol and an acid, with elimination of water, which contains the functional group carbon-oxygen double bond joined via carbon to another oxygen atom.

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