Cryptic crossword clue
Another nail in the coffin with Conservative leader screwing up – get irate 9

The most common and most likely answer to this crossword clue is the 9 letter word CIGARETTE

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Buddy explains!

The straight part
We know that "another nail in the coffin" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case another nail in the coffin = cigarette.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CIGARETTE mean?

CIGARETTE noun
  1. Tobacco or other substances, in a thin roll wrapped with paper, intended to be smoked.
CIGARETTE verb
  1. To give someone a cigarette, and/or to light one for them.

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