The most common and most likely answer to this crossword clue is the 5 letter word REACT
I've seen this crossword clue in Independent
R
E
A
C
T
More clues leading to the result REACT
- Cater for reform, and respond
- Trace different answer in response
- Return to the stage and do double-take?
- Give a response on law that’s passed
- What's done after engineers respond
- Play one's part again to produce a response
- Answer concerns area north of Connecticut
- Respond with regard to law
- Answer about a NE state
- Endlessly study court reply
Buddy explains!

The straight part
We know that "Answer" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case answer = react.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does REACT mean?
REACT noun- An emoji used to express a reaction to a post on social media.
- To act or perform a second time; to do over again; to reenact.
- To return an impulse or impression; to resist the action of another body by an opposite force
- To act upon each other; to exercise a reciprocal or a reverse effect, as two or more chemical agents; to act in opposition.
- To cause chemical agents to react; to cause one chemical agent to react with another.