Cryptic crossword clue
Antagonism in workplace? 10

The most common and most likely answer to this crossword clue is the 10 letter word OPPOSITION

I've seen this crossword clue in The Guardian
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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does OPPOSITION mean?

OPPOSITION noun
  1. The action of opposing or of being in conflict.
  2. An opposite or contrasting position.
  3. The apparent relative position of two celestial bodies when one is at an angle of 180 degrees from the other as seen from the Earth.
  4. A political party or movement opposed to the party or government in power.
  5. In United States intellectual property law, a proceeding in which an interested party seeks to prevent the registration of a trademark or patent.
  6. A position in which the player on the move must yield with his king allowing his opponent to advance with his own king.
  7. The difference of quantity or quality between two propositions having the same subject and predicate.

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