Cryptic crossword clue
Antagonistic business of country holding leading position 15

The most common and most likely answer to this crossword clue is the 15 letter word CONFRONTATIONAL

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Buddy explains!

The straight part
We know that "Antagonistic" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case antagonistic = confrontational.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONFRONTATIONAL mean?

CONFRONTATIONAL adjective
  1. Pertaining to a confrontation; characterized by, or given to initiating hostile encounter; in-your-face.

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