Cryptic crossword clue
Anticipating pierced hysterics over ITV comic 10

The most common and most likely answer to this crossword clue is the 10 letter word PREDICTIVE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Anticipating" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case anticipating = predictive.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PREDICTIVE mean?

PREDICTIVE adjective
  1. Useful in predicting.
  2. Describing a predictor.
  3. Expressing the expected accuracy of a statistical measure or of a diagnostic test.

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