The most common and most likely answer to this crossword clue is the 6 letter word DOWNER
I've seen this crossword clue in The Daily Telegraph
D
O
W
N
E
R
More clues leading to the result DOWNER
- Bad experience the end for Edward the Confessor?
- Might I be one necking booze?
- Unhappy experience of duke who makes confessions?
- Developed wonder drug
- Sedative offered as private parts turned red
- Duke, one with property, in depressing experience
- Antipathy that destroys wonder
- When hesitation follows a clue like this, it’s a depressing experience
- One who has to follow Germany’s depressing experience
- Private parts inflamed in retirement – a depressing experience
Buddy explains!
The straight part
We know that "Antipathy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case antipathy = downer.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DOWNER mean?
DOWNER noun- A negative drug trip.
- A drug that has depressant qualities.
- Something or someone disagreeable, dispiriting or depressing; a killjoy.
- A livestock animal that has collapsed.
- A form of industrial action in which workers down tools and refuse to work.