Cryptic crossword clue
Appease pair, needing sedative, going without it? 10

The most common and most likely answer to this crossword clue is the 10 letter word PROPITIATE

I've seen this crossword clue in The Times
P
R
O
P
I
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A
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Buddy explains!

The straight part
We know that "Appease" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case appease = propitiate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PROPITIATE mean?

PROPITIATE verb
  1. To conciliate, appease, or make peace with someone, particularly a god or spirit.
  2. To make propitious or favourable.
  3. To make propitiation.

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