Cryptic crossword clue
Argued contrarily as topless relations advanced 12

The most common and most likely answer to this crossword clue is the 12 letter word EXPOSTULATED

I've seen this crossword clue in The Times
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The straight part
We know that "Argued contrarily" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case argued contrarily = expostulated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EXPOSTULATED mean?

EXPOSTULATED verb
  1. To protest or remonstrate; to reason earnestly with a person on some impropriety of conduct.

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