The most common and most likely answer to this crossword clue is the 11 letter word WATERCOLOUR
I've seen this crossword clue in The Guardian
W
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More clues leading to the result WATERCOLOUR
Buddy explains!

The straight part
We know that "Artwork" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case artwork = watercolour.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WATERCOLOUR mean?
WATERCOLOUR noun- A water-soluble pigment.
- A painting made by using such pigment.
- This kind of painting as a genre.
- To paint using watercolour
- Pertaining to the methods or products of watercolor.