The most common and most likely answer to this crossword clue is the 2 plus 3 letter word MY BED
I've seen this crossword clue in The Guardian
M
Y
B
E
D
Buddy explains!
The straight part
We know that "Artwor/k (some say/)" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case artwor/k (some say/) = my bed.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.