Cryptic crossword clue
As to this charge: are you sure? 2,4,2

The most common and most likely answer to this crossword clue is the 2 plus 4 plus 2 letter word IS THAT SO

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Buddy explains!

The straight part
We know that "are you sure?" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case are you sure? = is that so.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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