The most common and most likely answer to this crossword clue is the 12 letter word DESPOLIATION
I've seen this crossword clue in The Guardian
D
E
S
P
O
L
I
A
T
I
O
N
Buddy explains!
The straight part
We know that "It’s what strippers do" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it’s what strippers do = despoliation.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DESPOLIATION mean?
DESPOLIATION noun- A stripping or plundering; spoliation.