Cryptic crossword clue
At the end, Spanish flu victim lost blood and so made to feel bad

The most common and most likely answer to this crossword clue is the 7 letter word HUMBLED

I've seen this crossword clue in The Guardian
H
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M
B
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Buddy explains!

The straight part
We know that "made to feel bad" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case made to feel bad = humbled.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HUMBLED mean?

HUMBLED verb
  1. To defeat or reduce the power, independence, or pride of
  2. To make humble or lowly; to make less proud or arrogant; to make meek and submissive.
HUMBLED adjective
  1. (usually qualifying a first-person pronoun) Grateful for the support of others, touched; honored, flattered.
  2. Overcome with humility; in awe of the strength of another or one's own weakness
HUMBLED verb
  1. Of an animal: to remove the horns; to poll.
  2. To separate (barley, oats, etc.) from the awns.

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