Cryptic crossword clue
Attacking what is believed by man – colic, so painful? 10

The most common and most likely answer to this crossword clue is the 10 letter word ICONOCLASM

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "Attacking what is believed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case attacking what is believed = iconoclasm.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ICONOCLASM mean?

ICONOCLASM noun
  1. The belief in, participation in, or sanction of destroying religious icons and other symbols or monuments, usually with religious or political motives.

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