The most common and most likely answer to this crossword clue is the 14 letter word BEATÂ AÂ RETREAT
I've seen this crossword clue in The Guardian
B
E
A
T
Â
A
Â
R
E
T
R
E
A
T
Buddy explains!
The straight part
We know that "make a run for it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case make a run for it = beat a retreat.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.