Cryptic crossword clue
Avoid this by not staying up too long, or else dad’s furious 6-4

The most common and most likely answer to this crossword clue is the 11 letter word SADDLE-SORE

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Avoid this by not staying up too long/Avoid this by not staying up too long" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case avoid this by not staying up too long/avoid this by not staying up too long = saddle-sore.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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