The most common and most likely answer to this crossword clue is the 4 letter word AKEE
I've seen this crossword clue in The Guardian
A
K
E
E
More clues leading to the result AKEE
Buddy explains!

The straight part
We know that "fruit" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case fruit = akee.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does AKEE mean?
AKEE noun- A tropical evergreen tree, Blighia sapida, related to the lychee and longan.
- The fruit of the tree, of which only the arils are edible, the remainder being poisonous.