Cryptic crossword clue
Awkward first drug dispute 6

The most common and most likely answer to this crossword clue is the 6 letter word STRIFE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "dispute" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case dispute = strife.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STRIFE mean?

STRIFE noun
  1. Striving; earnest endeavor; hard work.
  2. Exertion or contention for superiority, either by physical or intellectual means.
  3. Bitter conflict, sometimes violent.
  4. A trouble of any kind.
  5. That which is contended against; occasion of contest.

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