The most common and most likely answer to this crossword clue is the 1 letter word B
I've seen this crossword clue in The Guardian
B
More clues leading to the result B
- Live flies, very quietly eradicated in French city
- Airline to fly Bristol to N America
- twelve noon the natives swoon and no further work is done,
- Star of Brexit all washed up
- Bad vibe about second supporting film
- B
- 13 BARBITONE/SCROUNGES
- Wager Ireland should accept no abomination
- Film mob I’ve roused
- Burp mainly held in check by lawman with swelling ribcage?
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does B mean?
B adjective- Having from birth (or as if from birth) a certain quality or character; innate; inherited.