The most common and most likely answer to this crossword clue is the 4 letter word GUTS
I've seen this crossword clue in The Daily Telegraph
G
U
T
S
More clues leading to the result GUTS
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GUTS mean?
GUTS noun- The alimentary canal, especially the intestine.
- The abdomen of a person, especially one that is enlarged
- The intestines of an animal used to make strings of a tennis racket or violin, etc.
- A person's emotional, visceral self.
- A class that is not demanding or challenging.
- A narrow passage of water.
- The sac of silk taken from a silkworm when ready to spin its cocoon, for the purpose of drawing it out into a thread. When dry, it is exceedingly strong, and is used as the snood of a fishing line.
- To eviscerate.
- To remove or destroy the most important parts of.
- To show determination or courage (especially in the combination guts out).