Cryptic crossword clue
Barring margin pieces, played ligature in instrument 6

The most common and most likely answer to this crossword clue is the 6 letter word GUITAR

G
U
I
T
A
R


Buddy explains!

The straight part
We know that "instrument" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case instrument = guitar.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GUITAR mean?

GUITAR noun
  1. A stringed musical instrument, of European origin, usually with a fretted fingerboard and six strings, played with the fingers or a plectrum (guitar pick).
  2. Any type of musical instrument of the lute family, characterized by a flat back, along with a neck whose upper surface is in the same plane as the soundboard, with strings along the neck and parallel to the soundboard.
GUITAR verb
  1. To play the guitar.

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