Cryptic crossword clue
Be preoccupied with love and Elizabeth I having sex 6

The most common and most likely answer to this crossword clue is the 6 letter word OBSESS

O
B
S
E
S
S


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The straight part
We know that "be preoccupied with" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case be preoccupied with = obsess.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OBSESS mean?

OBSESS verb
  1. (passive, constructed with "with") To be preoccupied with a single topic or emotion.
  2. To dominate the thoughts of someone.
  3. (construed with over) To think or talk obsessively about.

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