The most common and most likely answer to this crossword clue is the 4 plus 3 letter word COME OFF
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More clues leading to the result COME OFF
Buddy explains!
The straight part
We know that "Be successful/give up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case be successful/give up = come off.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does COME OFF mean?
COME OFF noun- An outcome or conclusion; the way that a situation turns out.
- An evasive answer or postponement; an act of putting someone off.