Cryptic crossword clue
Bear toilet that's nasty? No, do this to it 10

The most common and most likely answer to this crossword clue is the 10 letter word OBLITERATE

I've seen this crossword clue in The Times
O
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The straight part
We know that "Bear toilet that's nasty? No, do this to it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case bear toilet that's nasty? no, do this to it = obliterate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OBLITERATE mean?

OBLITERATE verb
  1. To remove completely, leaving no trace; to wipe out; to destroy.

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