Cryptic crossword clue
Being short-handed, ultimately firm was shot 8

The most common and most likely answer to this crossword clue is the 8 letter word DWARFISM

D
W
A
R
F
I
S
M

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The straight part
We know that "Being short" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case being short = dwarfism.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DWARFISM mean?

DWARFISM noun
  1. The condition of being a dwarf.

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