The most common and most likely answer to this crossword clue is the 6 letter word SENORA
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More clues leading to the result SENORA
Buddy explains!
The straight part
We know that "Spanish lady" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spanish lady = senora.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SENORA mean?
SENORA noun- A Spanish term of address equivalent to Mrs., used alone or capitalized and prefixed to the name of a married, divorced or widowed woman