Cryptic crossword clue
Betrayals come from unbeliever, it is said

The most common and most likely answer to this crossword clue is the 12 letter word INFIDELITIES

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Betrayals" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case betrayals = infidelities.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INFIDELITIES mean?

INFIDELITIES noun
  1. Unfaithfulness in a marriage or an intimate relationship: practice or instance of having a sexual or romantic affair with someone other than one's spouse, without the consent of the spouse.
  2. Unfaithfulness in some other moral obligation.
  3. Lack of religious belief.

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