Cryptic crossword clue
Big business in Japan or South Africa, one mad on uranium 8

The most common and most likely answer to this crossword clue is the 8 letter word ZAIBATSU

Z
A
I
B
A
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U

Buddy explains!

The straight part
We know that "ig business in Japan" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ig business in japan = zaibatsu.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ZAIBATSU mean?

ZAIBATSU noun
  1. A Japanese ‘money clique’ or conglomerate; (by extension) in the United States, any large corporation.

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