Cryptic crossword clue
Big microphone comes from heavy metal 5

The most common and most likely answer to this crossword clue is the 5 letter word OSMIC

I've seen this crossword clue in The Guardian
O
S
M
I
C

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The straight part
We know that "from heavy metal" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case from heavy metal = osmic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OSMIC mean?

OSMIC adjective
  1. Pertaining to, derived from, or containing, osmium; specifically, designating those compounds in which it has a higher valence.

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