The most common and most likely answer to this crossword clue is the 6 letter word SICKER
I've seen this crossword clue in The Daily Telegraph
S
I
C
K
E
R
Buddy explains!
The straight part
We know that "more poorly" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case more poorly = sicker.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SICKER mean?
SICKER adjective- Having an urge to vomit.
- In poor health.
- Mentally unstable, disturbed.
- In bad taste.
- Tired of or annoyed by something.
- Very good, excellent, awesome, badass.
- In poor condition.
- Failing to sustain adequate harvests of crop, usually specified.
- (obsolete outside dialectal) Certain.
- (obsolete outside dialectal) Secure, safe.
- (obsolete outside dialectal) Certainly.
- (obsolete outside dialectal) Securely.
- To percolate, trickle, or ooze, as water through a crack.