The most common and most likely answer to this crossword clue is the 8 letter word STENOSIS
I've seen this crossword clue in Financial Times
S
T
E
N
O
S
I
S
More clues leading to the result STENOSIS
- Being unable to go to session abroad, ring off
- Blockage in passage or street accompanied by weird noises
- One’s after broken stones for narrowing of canal
- Blocking in passage when old-fashioned secretary and young girl meet
- Gun that’s very big is possible cause of blockage in passageway
- Secretaries facing one's stricture
Buddy explains!
The straight part
We know that "Blockage in passage" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case blockage in passage = stenosis.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does STENOSIS mean?
STENOSIS noun- An abnormal narrowing or stricture in a blood vessel or other tubular organ
- A reduction in capacity (physical or mental)