Cryptic crossword clue
Bloodsucker, reverse of direct going after pounds 5

The most common and most likely answer to this crossword clue is the 5 letter word LAMIA

L
A
M
I
A

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does LAMIA mean?

LAMIA noun
  1. A monster preying upon human beings and who sucked the blood of children, often described as having the head and breasts of a woman and the lower half of a serpent.

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