The most common and most likely answer to this crossword clue is the 11 letter word CLIFFHANGER
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Buddy explains!

The straight part
We know that "programme’s ending" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case programme’s ending = cliffhanger.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CLIFFHANGER mean?
CLIFFHANGER noun- An ending or stopping point calculated to leave a story unresolved, in order to create suspense.
- (by extension) An outcome which is awaited with keen anticipation, especially one which is delayed for a period of time or which is not known until the last minute.