The most common and most likely answer to this crossword clue is the 10 letter word DERMATITIS
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More clues leading to the result DERMATITIS
- Skin problem that could be almost dire at times
- Hide problem under mat — it isn’t entertaining
- Boob caught in cocked sidearm, which is irritating
- Rebellious talking horse is, after mating, in inflamed condition
- Complaint maitre d’ redressed, regularly wiping stains
- It smarted I fancy, producing irritation
- Doctor met diarist to make superficial complaint
Buddy explains!
The straight part
We know that "(something) which is irritating" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case (something) which is irritating = dermatitis.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DERMATITIS mean?
DERMATITIS noun- Inflammation of the skin.