The most common and most likely answer to this crossword clue is the 3 plus 4 letter word HOT CAKE
I've seen this crossword clue in Independent
H
O
T
C
A
K
E
More clues leading to the result HOT CAKE
Buddy explains!
The straight part
We know that "a best-seller" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a best-seller = hot cake.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.