Cryptic crossword clue
Book flight 6

The most common and most likely answer to this crossword clue is the 6 letter word EXODUS

I've seen this crossword clue in The Times
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Buddy explains!

The straight part
We know that "Book/flight" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case book/flight = exodus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EXODUS mean?

EXODUS noun
  1. A sudden departure of a large number of people.
EXODUS verb
  1. To depart from a place in a large group.

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